Business Fortune
PBS Biotech, headquartered in Camarillo, CA, USA, has positioned itself as a prominent player in the realm of cell therapy since its establishment in 2006. Specializing in single-use bioreactor systems and providing comprehensive process development services, the company has gained widespread recognition for its innovative solutions.
At the core of PBS Biotech's contributions to the industry lies the Vertical-Wheel bioreactor, a revolutionary technology tailored to meet the specific needs of cell therapy manufacturing. In contrast to traditional methods, this bioreactor offers scalability, enabling the manufacturing process to be customized according to diverse production requirements. This adaptability is crucial in the dynamic landscape of cell therapy, where varying production scales are often necessary.
A key advantage of the Vertical-Wheel bioreactor is its ability to streamline the process development for clients. This implies that companies utilizing PBS Biotech's technology can expedite their product development cycles, bringing therapies to market more efficiently. In the context of emerging treatments, where speed can directly impact patient outcomes, this rapid turnaround time holds significant importance.
PBS Biotech's Research and Development Facility
PBS Biotech's Bioprocess Research & Development team is renowned for its expertise in cell culture processes, catering to various therapeutic cell types such as iPSCs and MSCs. Operating from an advanced onsite laboratory, this team delivers exceptional contract process development services to clients worldwide.
- Expertise in Cell Culture: PBS Biotech's Bioprocess Research & Development team is globally recognized for its proficiency in cell culture processes, specializing in therapeutic cell types like iPSCs and MSCs.
- Exceptional Contract Process Development: Utilizing their advanced onsite laboratory, the team provides outstanding contract process development services to clients worldwide, ensuring high-quality outcomes.
- State-of-the-Art Facility: PBS Biotech operates within a cutting-edge 63,800 sq. ft. facility, equipped with a dedicated cleanroom and manufacturing areas. Here, they assemble single-use vessels and electro-mechanical bioreactors.
- Rigorous Quality Standards: All products undergo meticulous in-house assembly and inspection processes, guaranteeing they not only meet but exceed the highest quality standards in therapeutic cell manufacturing.
- Substantial Funding: In early 2023, PBS Biotech secured significant funding from leading investors such as Avego Management, LLC, and BroadOak Capital Partners. This funding infusion empowered the company to enhance its product portfolio and strengthen its process development capabilities, enabling global expansion and support for clients.
- Global Vision: PBS Biotech aims to become the global standard in manufacturing platforms for allogeneic cell-based therapies. Their mission is to facilitate potential cures for severe conditions like diabetes, cancer, and heart disease, demonstrating a strong commitment to innovation and quality.
- Advancing Cell Therapy: With an unwavering dedication to innovation and quality, PBS Biotech continues to drive advancements in the field of cell therapy, offering hope and potential solutions to patients worldwide.
Vertical-Wheel®: A New Paradigm for Suspension Cultures
Introducing a revolutionary approach to suspension cultures, the Vertical-Wheel® impeller stands as a groundbreaking innovation, providing an ideal fluid mixing environment for delicate therapeutic cells.
The Vertical-Wheel impeller, operating within a distinctive U-shaped vessel, achieves full suspension and gentle agitation of anchorage-dependent human cells, which are particularly sensitive to a bioreactor's hydrodynamic conditions. One of its critical advantages lies in the ability to consistently replicate cell culture processes and hydrodynamic conditions optimized at a small scale when scaling up to larger volumes.
Product Development: Ensure Your Best Possible Process
Ensure the excellence of your cell culture process with the expertise of their dedicated BioLab team, committed to tailoring scalable solutions precisely to your product and specifications. Benefit from the proficiency of PBS Biotech's scientists and chemical engineers, renowned for their industry-leading skills in developing cell culture procedures for a wide array of therapeutic cells. They specialize in creating scalable processes designed for seamless tech transfer. Clients have achieved significant milestones, including successfully scaling up Pluripotent Stem Cell (PSC) cultures, enabling a smooth progression into crucial first-in-human trials.
PBS Biotech stands is an example of proficiency and innovation. Its team of esteemed scientists and chemical engineers is renowned throughout the industry for their unparalleled skills in developing highly efficient and scalable processes for therapeutic cells. Their expertise extends across various cell types, enabling seamless tech transfer and propelling clients toward significant milestones, including successful progression into vital first-in-human trials.
Brian Lee, Ph.D. | Founder and CEO
Dr. Lee brings over 25 years of research, management, and leadership experience in biopharmaceutical R&D, bioprocess scale-up, and biomanufacturing with Amgen and Merck.
