Business Fortune
In a world where healthcare decisions impact millions of lives, having access to reliable, evidence-driven insights is non-negotiable. Aetion, founded in 2013, stands as an ideal of innovation, empowering life sciences companies, regulators, payers, and health technology agencies with the tools to make confident, data-backed decisions. Built on the fundamental truth that evidence must reflect the realities of all patient populations, not just those in clinical trials, Aetion has revolutionized healthcare decision-making through its powerful technology and expertise in real-world evidence (RWE).
A Mission to Drive Evidence-Based Healthcare
Aetion was born from a simple but profound vision: a value-based healthcare system demands real, actionable evidence. To deliver on this mission, Aetion combines decades of experience in epidemiology, health outcomes research, and cutting-edge technology. The result? The Aetion Evidence Platform® (AEP), a robust engine designed to tap into the untapped potential of real-world data (RWD) and turn it into actionable insights.
The company’s journey began when healthcare and technology experts joined forces to create solutions that address the critical gaps in traditional healthcare decision-making. From measuring long-term safety and efficacy to identifying cost-saving opportunities, Aetion’s platform streamlines the use of RWD at scale. Today, Aetion is trusted by global leaders in life sciences, regulators, and healthcare systems to deliver unparalleled clarity in a data-driven world.
Aetion Evidence Platform®: Powering Real-World Insights
At the heart of Aetion’s solutions lies the Aetion Evidence Platform® (AEP) – a state-of-the-art system tailored to manage and analyze real-world data seamlessly. AEP ensures transparency, consistency, and scientific rigor while enabling healthcare innovators to:
- Identify patient populations and treatment pathways
- Evaluate outcomes, trends, and cost-effectiveness
- Conduct regulatory-grade studies with reproducibility and speed
With built-in APIs and customizable applications, AEP simplifies even the most complex healthcare challenges. Its suite of applications includes Aetion Discover for descriptive analytics, Aetion Substantiate for decision-grade studies, and Aetion Generate for secure data management. Together, these tools empower stakeholders to make informed, evidence-based decisions that improve patient outcomes and drive innovation.
Setting the Gold Standard in Real-World Evidence
Aetion’s commitment to advancing the science of real-world evidence has positioned the company as a global leader. Their solutions are built with an unwavering focus on meeting regulatory standards, ensuring accuracy, and delivering results that matter.
With the rapid evolution of healthcare data and increasing demands from regulatory agencies, Aetion sets the benchmark for quality evidence generation. Their expertise spans critical areas such as:
- Comparative Effectiveness and Safety: Analyzing treatment outcomes to meet regulatory requirements and support pricing decisions.
- External Control Arms: Providing comparison data for single-arm clinical trials to demonstrate safety and effectiveness.
- Natural History Studies: Evaluating outcomes in real-world settings to guide trial design and pivotal study arguments.
- Post-Approval Safety Monitoring: Identifying and analyzing safety signals post-market approval to fulfill regulatory obligations.
With a proven record of delivering regulatory-grade evidence, Aetion enables clients to navigate complex healthcare landscapes with clarity and confidence.
The Experts behind the Science
Aetion’s team of over 100 scientists, data specialists, and regulatory experts forms the backbone of its success. Their collective decades of academic, industry, and government experience ensure that every study conducted through Aetion’s platform meets the highest scientific standards.
The company’s scientific services team works closely with clients to streamline evidence generation across product lifecycles. From initial feasibility assessments to full-scale regulatory submissions, Aetion’s experts ensure the right data, methodologies, and insights are in place to achieve success. Their trusted partnerships with global regulatory bodies, including the FDA, further underscore Aetion’s role as the standard-setter in RWE.
Driving Innovation in Healthcare Decision-Making
In an era where healthcare data is abundant but often underutilized, Aetion bridges the gap between raw information and actionable insights. The company’s innovative applications transform how real-world evidence is generated, evaluated, and shared. Whether it’s identifying unmet therapeutic needs, evaluating treatment pathways, or optimizing post-marketing safety studies, Aetion’s technology delivers answers that drive meaningful change.
Aetion’s impact extends beyond individual studies or decisions. By enabling healthcare stakeholders to use real-world data with precision and confidence, Aetion is shaping a future where healthcare systems are more effective, efficient, and equitable.
Partnering for Progress
Aetion’s partnerships with life sciences companies, regulators, and healthcare agencies are built on trust, collaboration, and a shared commitment to better patient outcomes. From addressing unmet medical needs to informing strategic pricing and formulary decisions, Aetion’s insights support innovation at every stage of the product lifecycle.
Their work spans critical areas, including:
- Research and development for new therapies
- Cost-effectiveness studies for pricing and market access
- Real-time adverse event analysis for safety monitoring
- Label expansion and post-approval evidence generation
By uniting expertise, technology, and real-world data, Aetion accelerates progress across the healthcare ecosystem.
Redefining Healthcare with Real-World Evidence
In a rapidly evolving industry, Aetion remains the partner of choice for organizations seeking clarity, confidence, and actionable results. Their innovative platform, unparalleled expertise, and unwavering commitment to scientific rigor have redefined what’s possible with real-world evidence.
Aetion’s mission to power critical healthcare decisions with evidence-driven technology continues to transform lives worldwide. With every study, insight, and partnership, Aetion brings the industry closer to a future where healthcare works for every patient, everywhere.
Jeremy Rassen, Sc.D. | Co-founder & Interim CEO
Jeremy is an epidemiologist and computer scientist with nearly 25 years of experience in the science and technology of big data.
He is Co-founder & Interim CEO of Aetion, a health care technology company that delivers real-world evidence for life sciences companies, payers, and regulatory agencies. He leads the Aetion team in their scientific research collaboration with FDA, which uses advanced analytical techniques to answer questions about the use of diagnostics and medications for COVID-19, and risk factors for COVID-19-related complications in patient populations.
Dr. Rassen is a Fellow of the International Society for Pharmacoepidemiology. He received his bachelor’s degree in Computer Science from Harvard College and his masters and doctorate degrees in Epidemiology from the Harvard T.H. Chan School of Public Health.
